Port Milwaukee is both an economic and logistical transportation hub for the Southeastern Wisconsin region, but is also home and center to some of the City of Milwaukee's major Lakefront events and community destinations, including:
- Summerfest, the world’s largest music festival, and other Milwaukee World Festivals hosted at the legendary Henry Maier Festival Park
- Discovery World, providing numerous educational opportunities and family-oriented activities in Milwaukee
- Multiple Great Lakes cruise berths near the heart of downtown Milwaukee, including the Pier Wisconsin Cruise Dock and the South Shore Cruise Dock
In addition, the Lake Express High Speed Car Ferry offers a crucial transportation option for passengers looking to quickly and conveniently cross Lake Michigan to Muskegon, Michigan while avoiding congested interstates in circumventing the Lake.